ELISA DKK1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regµLated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adµLt, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Immunogen:dickkopf homolog 1 Synonyms:Dickkopf 1, Dickkopf related protein 1, DKK 1, DKK1, hDkk 1, SK Observed MW:30-35 kDa Uniprot ID:O94907 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IF, IHC Recommended dilution:WB: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:10-1:100 Gene ID:22943 Research Area:Signal Transduction, Developmental biology